Nimble Protein Sequence Alignment in Grid (NPSAG)
نویسندگان
چکیده
منابع مشابه
Nimble Protein Sequence Alignment in Grid (NPSAG)
In Bio-Informatics application, the analysis of protein sequence is a kind of computation driven science which has rapidly and quickly growing biological data. Also databases used in these applications are heterogeneous in nature and alignment of protein sequence using physical techniques is expensive, slow and results are not always guaranteed/accurate. So this application requires crossplatfo...
متن کاملProtein multiple sequence alignment.
Protein sequence alignment is the task of identifying evolutionarily or structurally related positions in a collection of amino acid sequences. Although the protein alignment problem has been studied for several decades, many recent studies have demonstrated considerable progress in improving the accuracy or scalability of multiple and pairwise alignment tools, or in expanding the scope of task...
متن کاملProtein sequence alignment techniques.
The basic algorithms for alignment of two or more protein sequences are explained. Alternative methods for scoring substitutions and gaps (insertions and deletions) are described, as are global and local alignment methods. Multiple alignment techniques are explained, including methods for profile comparison. A summary is given of programs for the alignment and analysis of protein sequences, eit...
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Given the explosive growth of biological sequence databases and the computational complexity of aligning large sequences over extremely large databases most researchers have opted for utilizing the BLAST algorithm. While BLAST is completely appropriate for some purposes, the more rigorous and more computationally expensive Smith-Waterman algorithm is preferred for certain purposes. This work pr...
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Multiple sequence alignments are essential in computational analysis of protein sequences and structures, with applications in structure modeling, functional site prediction, phylogenetic analysis and sequence database searching. Constructing accurate multiple alignments for divergent protein sequences remains a difficult computational task, and alignment speed becomes an issue for large sequen...
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ژورنال
عنوان ژورنال: Journal of Computer Science
سال: 2008
ISSN: 1549-3636
DOI: 10.3844/jcssp.2008.36.41